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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620283
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Foxo1
Name: forkhead box O1
Acc ID: CHEBI:28744
Term: 2-hydroxy-17beta-estradiol
Definition: A 2-hydroxy steroid that consists of 17beta-estradiol having an additional hydroxy group at position 2.
Chemical ID: MESH:C001390
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Foxo1decreases expressionISOFOXO1 (Homo sapiens)6480464CTD2-hydroxyestradiol results in decreased expression of FOXO1 proteinPMID:23685341
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