GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | SPP1 | decreases expression | ISO | Spp1 (Mus musculus) | 6480464 | CTD | Sodium Fluoride results in decreased expression of SPP1 mRNA | PMID:27862939 | SPP1 | increases expression | ISO | Spp1 (Mus musculus) | 6480464 | CTD | Sodium Fluoride results in increased expression of SPP1 mRNA; Sodium Fluoride results in increased expression of SPP1 protein | PMID:35218729 | SPP1 | increases expression | ISO | Spp1 (Rattus norvegicus) | 6480464 | CTD | Sodium Fluoride results in increased expression of SPP1 protein | PMID:23933529 | SPP1 | multiple interactions | ISO | Spp1 (Mus musculus) | 6480464 | CTD | BMP2 protein affects the reaction [Sodium Fluoride results in increased expression of SPP1 mRNA]; BMP2 protein affects the reaction [Sodium Fluoride results in increased expression of SPP1 protein]; CTNNB1 protein affects the reaction [BMP2 protein affects the reaction [Sodium Fluoride results in increased expression of SPP1 mRNA]]; CTNNB1 protein affects the reaction [BMP2 protein affects the reaction [Sodium Fluoride results in increased expression of SPP1 protein]] | PMID:35218729 | SPP1 | multiple interactions | ISO | Spp1 (Rattus norvegicus) | 6480464 | CTD | Sodium Fluoride inhibits the reaction [Gentamicins results in increased expression of SPP1 mRNA]; Sodium Fluoride inhibits the reaction [Gentamicins results in increased expression of SPP1 protein] | PMID:26779593 | | ||||||||||||||||||||||
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