GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdkn1a | affects expression | ISO | Cdkn1a (Mus musculus) | 6480464 | CTD | Sodium Fluoride affects the expression of CDKN1A protein | PMID:30738887 | Cdkn1a | decreases expression | ISO | CDKN1A (Homo sapiens) | 6480464 | CTD | Sodium Fluoride results in decreased expression of CDKN1A mRNA; Sodium Fluoride results in decreased expression of CDKN1A protein | PMID:31669217 | Cdkn1a | increases expression | ISO | CDKN1A (Homo sapiens) | 6480464 | CTD | Sodium Fluoride results in increased expression of CDKN1A mRNA; Sodium Fluoride results in increased expression of CDKN1A protein | PMID:22525295 | Cdkn1a | increases methylation | ISO | CDKN1A (Homo sapiens) | 6480464 | CTD | Sodium Fluoride results in increased methylation of CDKN1A promoter | PMID:31669217 | Cdkn1a | multiple interactions | ISO | Cdkn1a (Mus musculus) | 6480464 | CTD | SRT1720 affects the reaction [Sodium Fluoride affects the expression of CDKN1A protein] | PMID:30738887 | Cdkn1a | multiple interactions | ISO | CDKN1A (Homo sapiens) | 6480464 | CTD | Decitabine inhibits the reaction [Sodium Fluoride results in decreased expression of CDKN1A mRNA]; Decitabine inhibits the reaction [Sodium Fluoride results in decreased expression of CDKN1A protein]; Decitabine inhibits the reaction [Sodium Fluoride results in increased methylation of CDKN1A promoter] | PMID:31669217 | |
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