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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557448
Species: Mus musculus
RGD Object: Gene
Symbol: Top2b
Name: topoisomerase (DNA) II beta
Acc ID: CHEBI:28714
Term: S-butyl-DL-homocysteine (S,R)-sulfoximine
Definition: A sulfoximide that is the sulfoximine derivative of an analogue of DL-methionine in which the S-methyl group is replaced by S-butyl.
Chemical ID: MESH:D019328
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Top2bdecreases expressionEXP 6480464CTDButhionine Sulfoximine results in decreased expression of TOP2B mRNA

PMID:15707499
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