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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318015
Species: Mus musculus
RGD Object: Gene
Symbol: Nlrp3
Name: NLR family, pyrin domain containing 3
Acc ID: CHEBI:28714
Term: S-butyl-DL-homocysteine (S,R)-sulfoximine
Definition: A sulfoximide that is the sulfoximine derivative of an analogue of DL-methionine in which the S-methyl group is replaced by S-butyl.
Chemical ID: MESH:D019328
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nlrp3multiple interactionsEXP 6480464CTD[Phenytoin co-treated with Buthionine Sulfoximine] results in increased expression of NLRP3 mRNAPMID:23986454
Nlrp3multiple interactionsISONlrp3 (Rattus norvegicus)6480464CTD[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of NLRP3 mRNAPMID:26177832
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