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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737520
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp19a1
Name: cytochrome P450, family 19, subfamily a, polypeptide 1
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp19a1affects expressionISOCYP19A1 (Homo sapiens)6480464CTDCopper affects the expression of CYP19A1 mRNAPMID:34871762
Cyp19a1increases expressionISOCYP19A1 (Homo sapiens)6480464CTDCopper results in increased expression of CYP19A1 mRNAPMID:30641075
Cyp19a1multiple interactionsISOCYP19A1 (Homo sapiens)6480464CTDCopper inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]; Copper promotes the reaction [[FSH-BI protein, human analog co-treated with FSHB protein] results in decreased expression of CYP19A1 mRNA]PMID:34871762
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