GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | APOE | affects binding | EXP | | 6480464 | CTD | APOE protein binds to Copper | PMID:23896426 | APOE | decreases expression | ISO | Apoe (Rattus norvegicus) | 6480464 | CTD | Copper results in decreased expression of APOE mRNA | PMID:22465980 | APOE | increases expression | ISO | Apoe (Rattus norvegicus) | 6480464 | CTD | Copper deficiency results in increased expression of APOE mRNA | PMID:19821111 | APOE | increases uptake | ISO | Apoe (Mus musculus) | 6480464 | CTD | APOE gene mutant form results in increased uptake of Copper | PMID:25749341 | |
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