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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733968
Species: Homo sapiens
RGD Object: Gene
Symbol: IKBKB
Name: inhibitor of nuclear factor kappa B kinase subunit beta
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IKBKBmultiple interactionsEXP 6480464CTD[Chelating Agents binds to Copper] which results in increased expression of IKBKB mRNA; [N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide results in decreased activity of IKBKB protein] which results in decreased susceptibility to CopperPMID:19747488 PMID:30911355
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