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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733803
Species: Homo sapiens
RGD Object: Gene
Symbol: GADD45A
Name: growth arrest and DNA damage inducible alpha
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GADD45Amultiple interactionsEXP 6480464CTD[Chelating Agents binds to Copper] which results in increased expression of GADD45A mRNA; [NSC 689534 binds to Copper] which results in increased expression of GADD45A mRNAPMID:20971185 PMID:30911355
GADD45Adecreases expressionISOGadd45a (Rattus norvegicus)6480464CTDCopper results in decreased expression of GADD45A mRNAPMID:30556269
GADD45Aincreases expressionISOGadd45a (Rattus norvegicus)6480464CTDCopper results in increased expression of GADD45A mRNAPMID:22465980
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