GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | B2m | multiple interactions | ISO | B2m (Mus musculus) | 6480464 | CTD | [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of B2M mRNA; MT1 affects the reaction [Copper results in increased expression of B2M mRNA]; MT2 affects the reaction [Copper results in increased expression of B2M mRNA] | PMID:15467011 PMID:16629173 | B2m | multiple interactions | ISO | B2M (Homo sapiens) | 6480464 | CTD | Copper binds to and results in decreased folding of and results in decreased stability of B2M protein; Copper promotes the reaction [B2M protein binds to B2M protein]; Urea promotes the reaction [Copper promotes the reaction [B2M protein binds to B2M protein]] | PMID:16513784 PMID:17254602 | |
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