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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1588455
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Thbs1
Name: thrombospondin 1
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Thbs1increases expressionISOThbs1 (Mus musculus)6480464CTDCopper results in increased expression of THBS1 mRNAPMID:16629173
Thbs1multiple interactionsISOTHBS1 (Homo sapiens)6480464CTD[Chelating Agents binds to Copper] which affects the expression of THBS1 mRNA; [NSC 689534 binds to Copper] which results in increased expression of THBS1 mRNAPMID:20971185 PMID:30911355
Thbs1multiple interactionsISOThbs1 (Mus musculus)6480464CTD[ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of THBS1 mRNAPMID:15467011
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