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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349475
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPA1A
Name: heat shock protein family A (Hsp70) member 1A
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPA1Aincreases expressionEXP 6480464CTDCopper results in increased expression of HSPA1A mRNAPMID:17244614
HSPA1Amultiple interactionsEXP 6480464CTD[Disulfiram binds to Copper] which results in decreased expression of HSPA1A mRNA; [Organoselenium Compounds binds to Copper] which results in increased expression of HSPA1A mRNAPMID:24690739 PMID:25167922
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