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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1321287
Species: Homo sapiens
RGD Object: Gene
Symbol: HNRNPA2B1
Name: heterogeneous nuclear ribonucleoprotein A2/B1
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HNRNPA2B1affects bindingEXP 6480464CTDHNRNPA2B1 protein binds to CopperPMID:15359738
HNRNPA2B1multiple interactionsEXP 6480464CTD[Disulfiram binds to Copper] which results in increased expression of HNRNPA2B1 mRNA; [NSC 689534 binds to Copper] which results in decreased expression of HNRNPA2B1 mRNAPMID:20971185 PMID:24690739
HNRNPA2B1affects localizationISOHnrnpa2b1 (Mus musculus)6480464CTDCopper affects the localization of HNRNPA2B1 proteinPMID:21146535
HNRNPA2B1affects splicingISOHnrnpa2b1 (Mus musculus)6480464CTDCopper affects the splicing of HNRNPA2B1 mRNAPMID:21146535
HNRNPA2B1increases expressionISOHnrnpa2b1 (Mus musculus)6480464CTDCopper results in increased expression of HNRNPA2B1 mRNA; Copper results in increased expression of HNRNPA2B1 mRNA alternative form; Copper results in increased expression of HNRNPA2B1 protein alternative formPMID:16629173 PMID:21146535
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