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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311639
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cryz
Name: crystallin zeta
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cryzincreases activityISOCryz (Mus musculus)6480464CTDCopper results in increased activity of CRYZ proteinPMID:15297030
Cryzmultiple interactionsISOCRYZ (Homo sapiens)6480464CTD[NSC 689534 binds to Copper] which results in decreased expression of CRYZ mRNAPMID:20971185
Cryzmultiple interactionsISOCryz (Mus musculus)6480464CTDCopper inhibits the reaction [Benzo(a)pyrene results in increased expression of CRYZ mRNA]; Copper inhibits the reaction [beta-Naphthoflavone results in increased activity of CRYZ protein]; Copper inhibits the reaction [beta-Naphthoflavone results in increased expression of CRYZ mRNA]; Copper inhibits the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Copper inhibits the reaction [Methylcholanthrene results in increased expression of CRYZ mRNA]; Copper inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CRYZ protein]; Copper inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CRYZ mRNA]PMID:15297030
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