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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345007
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP2E1
Name: cytochrome P450 family 2 subfamily E member 1
Acc ID: CHEBI:28638
Term: isobutyronitrile
Definition: An aliphatic nitrile that is acetonitrile in which two of the hydrogens have been replaced by methyl groups.
Chemical ID: MESH:C022246
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP2E1increases response to substanceISOCyp2e1 (Mus musculus)6480464CTDCYP2E1 protein results in increased susceptibility to isobutyronitrilePMID:22051853
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