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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732222
Species: Mus musculus
RGD Object: Gene
Symbol: Gsr
Name: glutathione reductase
Acc ID: CHEBI:28619
Term: acrylamide
Definition: A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia.
Chemical ID: MESH:D020106
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsrincreases activityISOGSR (Homo sapiens)6480464CTDAcrylamide results in increased activity of GSR proteinPMID:21777647
Gsrincreases expressionISOGSR (Homo sapiens)6480464CTDAcrylamide results in increased expression of GSR mRNAPMID:32763439
Gsrmultiple interactionsISOGSR (Homo sapiens)6480464CTD3,4-dihydroxyphenylethanol inhibits the reaction [Acrylamide results in increased activity of GSR protein]PMID:21777647
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