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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731551
Species: Homo sapiens
RGD Object: Gene
Symbol: GCLM
Name: glutamate-cysteine ligase modifier subunit
Acc ID: CHEBI:28619
Term: acrylamide
Definition: A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia.
Chemical ID: MESH:D020106
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GCLMdecreases expressionEXP 6480464CTDAcrylamide results in decreased expression of GCLM mRNAPMID:28159594
GCLMincreases expressionEXP 6480464CTDAcrylamide results in increased expression of GCLM mRNAPMID:32763439
GCLMmultiple interactionsEXP 6480464CTDsalvin inhibits the reaction [Acrylamide results in decreased expression of GCLM mRNA]PMID:28159594
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