Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69152
Species: Homo sapiens
RGD Object: Gene
Symbol: EGFR
Name: epidermal growth factor receptor
Acc ID: CHEBI:28619
Term: acrylamide
Definition: A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia.
Chemical ID: MESH:D020106
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EGFRaffects phosphorylationEXP 6480464CTDAcrylamide analog affects the phosphorylation of EGFR proteinPMID:11462982
EGFRdecreases phosphorylationEXP 6480464CTDAcrylamide analog results in decreased phosphorylation of EGFR proteinPMID:10753475
EGFRincreases expressionEXP 6480464CTDAcrylamide results in increased expression of EGFR proteinPMID:24508477
EGFRmultiple interactionsEXP 6480464CTDCurcumin inhibits the reaction [Acrylamide results in increased expression of EGFR protein]; epigallocatechin gallate inhibits the reaction [Acrylamide results in increased expression of EGFR protein]PMID:24508477
Go Back to source page   Continue to Ontology report