Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tp53
Name: tumor protein p53
Acc ID: CHEBI:28619
Term: acrylamide
Definition: A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia.
Chemical ID: MESH:D020106
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tp53increases expressionEXP 6480464CTDAcrylamide results in increased expression of TP53 mRNAPMID:36598108
Tp53multiple interactionsEXP 6480464CTDnaringin inhibits the reaction [Acrylamide results in increased expression of TP53 mRNA]PMID:36598108
Tp53increases expressionISOTrp53 (Mus musculus)6480464CTDAcrylamide results in increased expression of TRP53 mRNA; Acrylamide results in increased expression of TRP53 proteinPMID:25531190 PMID:28067054 PMID:34906654
Tp53increases expressionISOTP53 (Homo sapiens)6480464CTDAcrylamide results in increased expression of TP53 protein modified formPMID:20734998
Tp53increases mutagenesisISOTP53 (Homo sapiens)6480464CTDAcrylamide results in increased mutagenesis of TP53 genePMID:15240786
Tp53multiple interactionsISOTrp53 (Mus musculus)6480464CTDATF3 protein promotes the reaction [Acrylamide results in increased expression of TRP53 protein]PMID:25531190
Tp53multiple interactionsISOTP53 (Homo sapiens)6480464CTDAcrylamide results in increased phosphorylation of and results in increased expression of TP53 proteinPMID:19426797
Go Back to source page   Continue to Ontology report