GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | increases activity | EXP | | 6480464 | CTD | Acrylamide results in increased activity of CASP3 protein | PMID:27920337 PMID:29607694 | Casp3 | increases expression | EXP | | 6480464 | CTD | Acrylamide results in increased expression of CASP3 mRNA; Acrylamide results in increased expression of CASP3 protein | PMID:22459607 PMID:28056603 PMID:36598108 | Casp3 | multiple interactions | EXP | | 6480464 | CTD | epigallocatechin gallate inhibits the reaction [Acrylamide results in increased activity of CASP3 protein]; epigallocatechin gallate inhibits the reaction [Acrylamide results in increased expression of CASP3 protein]; naringin inhibits the reaction [Acrylamide results in increased expression of CASP3 protein]; Taurine inhibits the reaction [Acrylamide results in increased activity of CASP3 protein] | PMID:27920337 PMID:28056603 PMID:29607694 PMID:36598108 | Casp3 | affects expression | ISO | Casp3 (Mus musculus) | 6480464 | CTD | Acrylamide affects the expression of CASP3 mRNA | PMID:28067054 | Casp3 | increases activity | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Acrylamide results in increased activity of CASP3 protein | PMID:19475399 PMID:21777647 | Casp3 | increases cleavage | ISO | Casp3 (Mus musculus) | 6480464 | CTD | Acrylamide results in increased cleavage of CASP3 protein | PMID:37172712 | Casp3 | increases expression | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Acrylamide results in increased expression of CASP3 mRNA | PMID:28159594 | Casp3 | multiple interactions | ISO | Casp3 (Mus musculus) | 6480464 | CTD | TFEB protein inhibits the reaction [Acrylamide results in increased cleavage of CASP3 protein] | PMID:37172712 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | 3,4-dihydroxyphenylethanol inhibits the reaction [Acrylamide results in increased activity of CASP3 protein]; salvin inhibits the reaction [Acrylamide results in increased expression of CASP3 mRNA]; tris(dicarboxymethylene)fullerene-C3 inhibits the reaction [Acrylamide results in increased activity of CASP3 protein] | PMID:19475399 PMID:21777647 PMID:28159594 | | ||||||||||||||||||||||
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