GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Foxo3 | increases expression | EXP | | 6480464 | CTD | Acrylamide results in increased expression of FOXO3 mRNA; Acrylamide results in increased expression of FOXO3 protein | PMID:33582169 | Foxo3 | multiple interactions | EXP | | 6480464 | CTD | [FOXO3 mRNA co-treated with Acrylamide] results in decreased expression of CCND1 protein; [FOXO3 mRNA co-treated with Acrylamide] results in increased expression of CDKN1A protein; [MIR193B mRNA co-treated with Acrylamide] results in decreased expression of FOXO3 protein; FOXO3 protein promotes the reaction [Acrylamide results in decreased expression of CCND1 mRNA]; FOXO3 protein promotes the reaction [Acrylamide results in increased expression of CDKN1A mRNA]; MIR193B mRNA inhibits the reaction [Acrylamide results in increased expression of FOXO3 mRNA] | PMID:33582169 | |
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