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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10700
Species: Mus musculus
RGD Object: Gene
Symbol: Gstt1
Name: glutathione S-transferase, theta 1
Acc ID: CHEBI:28619
Term: acrylamide
Definition: A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia.
Chemical ID: MESH:D020106
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gstt1affects metabolic processingISOGSTT1 (Homo sapiens)6480464CTDGSTT1 gene polymorphism affects the metabolism of AcrylamidePMID:19131562
Gstt1increases expressionISOGstt1 (Rattus norvegicus)6480464CTDAcrylamide results in increased expression of GSTT1 mRNAPMID:28959563
Gstt1multiple interactionsISOGSTT1 (Homo sapiens)6480464CTD[CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the metabolism of AcrylamidePMID:19131562
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