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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10230
Species: Mus musculus
RGD Object: Gene
Symbol: Bcl2
Name: B cell leukemia/lymphoma 2
Acc ID: CHEBI:28619
Term: acrylamide
Definition: A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia.
Chemical ID: MESH:D020106
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionEXP 6480464CTDAcrylamide results in decreased expression of BCL2 mRNA; Acrylamide results in decreased expression of BCL2 proteinPMID:28067054 PMID:34906654 PMID:37172712
Bcl2multiple interactionsEXP 6480464CTDTFEB protein inhibits the reaction [Acrylamide results in decreased expression of BCL2 protein]PMID:37172712
Bcl2decreases expressionISOBcl2 (Rattus norvegicus)6480464CTDAcrylamide results in decreased expression of BCL2 mRNA; Acrylamide results in decreased expression of BCL2 proteinPMID:27920337 PMID:28056603 PMID:28959563 PMID:29607694
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDAcrylamide results in decreased expression of BCL2 mRNAPMID:32763439
Bcl2multiple interactionsISOBcl2 (Rattus norvegicus)6480464CTDepigallocatechin gallate inhibits the reaction [Acrylamide results in decreased expression of BCL2 protein]; Taurine inhibits the reaction [Acrylamide results in decreased expression of BCL2 protein]PMID:28056603 PMID:29607694
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