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RGD ID: 620545
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chek1
Name: checkpoint kinase 1
Acc ID: CHEBI:28544
Term: digitoxin
Definition: A cardenolide glycoside in which the 3beta-hydroxy group of digitoxigenin carries a 2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl trisaccharide chain.
Chemical ID: MESH:D004074
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chek1decreases expressionISORGD:7322926480464CTDDigitoxin analog results in decreased expression of CHEK1 protein Digitoxin results in decreased expression of CHEK1 protein

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