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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3171
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfkbia
Name: NFKB inhibitor alpha
Acc ID: CHEBI:28544
Term: digitoxin
Definition: A cardenolide glycoside in which the 3beta-hydroxy group of digitoxigenin carries a 2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl trisaccharide chain.
Chemical ID: MESH:D004074
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkbiadecreases phosphorylationISORGD:7354406480464CTDDigitoxin results in decreased phosphorylation of NFKBIA protein

PMID:15136726
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