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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2321863
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fanci
Name: FA complementation group I
Acc ID: CHEBI:28544
Term: digitoxin
Definition: A cardenolide glycoside in which the 3beta-hydroxy group of digitoxigenin carries a 2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl trisaccharide chain.
Chemical ID: MESH:D004074
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fancimultiple interactionsISORGD:16053806480464CTDDigitoxin inhibits the reaction [Mitomycin results in increased expression of and affects the ubiquitination of FANCI protein]

PMID:24124520
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