GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | decreases expression | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Digitoxin analog results in decreased expression of CASP3 protein; Digitoxin results in decreased expression of CASP3 protein | PMID:22037315 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Digitoxin affects the reaction [HIF1A protein affects the cleavage of CASP3 protein]; Digitoxin affects the reaction [STAT3 protein affects the cleavage of CASP3 protein]; HIF1A protein affects the reaction [Digitoxin affects the reaction [STAT3 protein affects the cleavage of CASP3 protein]]; STAT3 protein affects the reaction [Digitoxin affects the reaction [HIF1A protein affects the cleavage of CASP3 protein]] | PMID:34717917 | |
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