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RGD ID: 10669
Species: Mus musculus
RGD Object: Gene
Symbol: Gnas
Name: GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
Acc ID: CHEBI:28487
Term: reserpine
Definition: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Chemical ID: MESH:D012110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:27166480464CTDReserpine results in decreased expression of GNAS protein alternative form

increases expressionISORGD:27166480464CTDReserpine results in increased expression of GNAS mRNA, Reserpine results in increased expression of GNAS protein

PMID:11264240, PMID:8419537
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.