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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2901
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il6
Name: interleukin 6
Acc ID: CHEBI:28412
Term: eriodictyol
Definition: A tetrahydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 7, 3' and 4' respectively.
Chemical ID: MESH:C007619
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il6multiple interactionsISORGD:108026480464CTDeriodictyol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] eriodictyol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]

PMID:21544733 PMID:31860763
Il6multiple interactionsISORGD:13525826480464CTDeriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]

PMID:20438634
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