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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303284
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Acc ID: CHEBI:28411
Term: allicin
Definition: A botanical anti-fungal agent that has formula C6H10OS2.
Chemical ID: MESH:C006452
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpa1increases activityEXP 6480464CTDallicin results in increased activity of TRPA1 proteinPMID:17684094
Trpa1multiple interactionsEXP 6480464CTD[allicin binds to and results in increased activity of TRPA1 protein] which results in increased transport of Calcium; allicin binds to and results in increased activity of TRPA1 proteinPMID:20086034
Trpa1multiple interactionsISOTrpa1 (Mus musculus)6480464CTDallicin binds to and results in increased activity of TRPA1 proteinPMID:17825279
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