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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2475
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2e1
Name: cytochrome P450, family 2, subfamily e, polypeptide 1
Acc ID: CHEBI:28398
Term: butan-2-one
Definition: A dialkyl ketone that is a four-carbon ketone carrying a single keto- group at position C-2.
Chemical ID: MESH:C005222
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2e1affects response to substanceISORGD:13450076480464CTDCYP2E1 gene mutant form affects the susceptibility to methylethyl ketone

PMID:21352904
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.