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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68594
Species: Homo sapiens
RGD Object: Gene
Symbol: EPAS1
Name: endothelial PAS domain protein 1
Acc ID: CHEBI:28393
Term: beta-D-glucosamine
Definition: A 2-amino-2-deoxy-D-glucopyranose that is D-glucosamine having a beta-configuration at the anomeric position.
Chemical ID: MESH:D005944
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EPAS1decreases expressionISOEpas1 (Rattus norvegicus)6480464CTDGlucosamine results in decreased expression of EPAS1 mRNAPMID:17109745
EPAS1multiple interactionsISOEpas1 (Rattus norvegicus)6480464CTDGlucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA]PMID:17109745
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