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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348077
Species: Homo sapiens
RGD Object: Gene
Symbol: CASP12
Name: caspase 12 (gene/pseudogene)
Acc ID: CHEBI:28304
Term: heparin
Definition: A highly sulfated linear glycosaminoglycan comprising complex patterns of uronic acid-(1->4)-D-glucosamine repeating subunits. Used as an injectable anticoagulant, it has the highest negative charge density of any known biological molecule.
Chemical ID: MESH:D006493
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP12multiple interactionsISOCasp12 (Mus musculus)6480464CTDHeparin inhibits the reaction [Paraoxon results in increased expression of and affects the activity of CASP12 protein]; Heparin inhibits the reaction [Paraoxon results in increased expression of CASP12 protein]PMID:20079824 PMID:26998625
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