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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735868
Species: Homo sapiens
RGD Object: Gene
Symbol: NQO1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:28299
Term: quercetin 3-O-beta-D-glucofuranoside
Definition: A quercetin O-glucoside in which a glucofuranosyl residue is attached at position 3 of quercetin via a beta-glycosidic linkage.
Chemical ID: MESH:C016527
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:25036480464CTD[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of NQO1 mRNA, isoquercitrin analog inhibits the reaction [Propylthiouracil results in increased expression of NQO1 mRNA]

PMID:20033131, PMID:31068541
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.