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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352582
Species: Homo sapiens
RGD Object: Gene
Symbol: IL6
Name: interleukin 6
Acc ID: CHEBI:28266
Term: fluorene
Definition: An ortho-fused tricyclic hydrocarbon that is a major component of fossil fuels and their derivatives
Chemical ID: MESH:C041509
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL6increases expressionEXP 6480464CTDfluorene results in increased expression of IL6 mRNA; fluorene results in increased expression of IL6 proteinPMID:32856796
IL6multiple interactionsEXP 6480464CTD[fluorene co-treated with phenanthrene] results in increased expression of IL6 mRNA; [fluorene co-treated with phenanthrene] results in increased expression of IL6 proteinPMID:32856796
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