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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10136
Species: Mus musculus
RGD Object: Gene
Symbol: Alb
Name: albumin
Acc ID: CHEBI:28262
Term: dimethyl sulfoxide
Definition: A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Chemical ID: MESH:D004121
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Albdecreases expressionISOAlb (Rattus norvegicus)6480464CTDDimethyl Sulfoxide results in decreased expression of ALB mRNA; Dimethyl Sulfoxide results in decreased expression of ALB proteinPMID:14757319
Albdecreases expressionISOALB (Homo sapiens)6480464CTDDimethyl Sulfoxide results in decreased expression of ALB mRNAPMID:22105179
Albmultiple interactionsISOALB (Homo sapiens)6480464CTD[Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of ALB mRNA; [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased secretion of ALB proteinPMID:35366062
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