GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | increases expression | EXP | | 6480464 | CTD | Galactose results in increased expression of CASP3 protein | PMID:32295448 PMID:34673010 | Casp3 | multiple interactions | EXP | | 6480464 | CTD | [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; Melatonin inhibits the reaction [Galactose results in increased expression of CASP3 protein] | PMID:25997894 PMID:34673010 | Casp3 | increases activity | ISO | Casp3 (Mus musculus) | 6480464 | CTD | Galactose results in increased activity of CASP3 protein | PMID:23795773 | Casp3 | increases cleavage | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Galactose results in increased cleavage of CASP3 protein | PMID:23036742 | Casp3 | increases expression | ISO | Casp3 (Mus musculus) | 6480464 | CTD | Galactose results in increased expression of CASP3 mRNA | PMID:33761044 | Casp3 | multiple interactions | ISO | Casp3 (Mus musculus) | 6480464 | CTD | albicanol inhibits the reaction [Galactose results in increased expression of CASP3 mRNA]; Pioglitazone inhibits the reaction [Galactose results in increased activity of CASP3 protein] | PMID:23795773 PMID:33761044 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Phycocyanin inhibits the reaction [Galactose results in increased cleavage of CASP3 protein] | PMID:23036742 | |
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