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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621016
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pde7b
Name: phosphodiesterase 7B
Acc ID: CHEBI:28241
Term: papaverine
Definition: A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Chemical ID: MESH:D010208
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pde7bmultiple interactionsISOPde7b (Mus musculus)6480464CTDPapaverine inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]PMID:10618442
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