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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732095
Species: Mus musculus
RGD Object: Gene
Symbol: Pcna
Name: proliferating cell nuclear antigen
Acc ID: CHEBI:28230
Term: hesperetin
Definition: A trihydroxyflavanone having the three hydroxy gropus located at the 3'-, 5- and 7-positions and an additional methoxy substituent at the 4'-position.
Chemical ID: MESH:C013015
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pcnamultiple interactionsEXP 6480464CTDhesperetin inhibits the reaction [Benzo(a)pyrene results in increased expression of PCNA protein]PMID:26546711
Pcnamultiple interactionsISOPcna (Rattus norvegicus)6480464CTDhesperetin inhibits the reaction [Doxorubicin results in decreased expression of PCNA mRNA]PMID:34933056
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