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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733100
Species: Homo sapiens
RGD Object: Gene
Symbol: BCL2
Name: BCL2 apoptosis regulator
Acc ID: CHEBI:28217
Term: acrylonitrile
Definition: A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by an ethenyl group.
Chemical ID: MESH:D000181
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BCL2decreases expressionEXP 6480464CTDAcrylonitrile results in decreased expression of BCL2 proteinPMID:16173056
BCL2decreases expressionISOBcl2 (Mus musculus)6480464CTDAcrylonitrile results in decreased expression of BCL2 mRNA; Acrylonitrile results in decreased expression of BCL2 proteinPMID:35429547
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