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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732740
Species: Homo sapiens
RGD Object: Gene
Symbol: CAT
Name: catalase
Acc ID: CHEBI:28217
Term: acrylonitrile
Definition: A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by an ethenyl group.
Chemical ID: MESH:D000181
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CATdecreases activityISOCat (Rattus norvegicus)6480464CTDAcrylonitrile results in decreased activity of CAT proteinPMID:19913070 PMID:20127315
CATincreases expressionISOCat (Mus musculus)6480464CTDAcrylonitrile results in increased expression of CAT proteinPMID:35429547
CATmultiple interactionsISOCat (Rattus norvegicus)6480464CTDCurcumin inhibits the reaction [Acrylonitrile results in decreased activity of CAT protein]PMID:19913070
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