GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sqstm1 | affects response to substance | EXP | | 6480464 | CTD | SQSTM1 protein affects the susceptibility to methylmercuric chloride | PMID:37258240 | Sqstm1 | increases expression | EXP | | 6480464 | CTD | methylmercuric chloride results in increased expression of SQSTM1 protein | PMID:27667695 | Sqstm1 | multiple interactions | EXP | | 6480464 | CTD | [Docosahexaenoic Acids co-treated with methylmercuric chloride] results in increased expression of SQSTM1 mRNA; [Eicosapentaenoic Acid co-treated with methylmercuric chloride] results in increased expression of SQSTM1 mRNA; [methylmercuric chloride co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of SQSTM1 protein; ATG5 promotes the reaction [methylmercuric chloride results in increased expression of SQSTM1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [SQSTM1 protein affects the susceptibility to methylmercuric chloride]; Chloroquine affects the reaction [SQSTM1 protein affects the susceptibility to methylmercuric chloride]; Eicosapentaenoic Acid inhibits the reaction [[Docosahexaenoic Acids co-treated with methylmercuric chloride] results in increased expression of SQSTM1 mRNA]; methylmercuric chloride promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SQSTM1 mRNA]; pyrazolanthrone inhibits the reaction [methylmercuric chloride results in increased expression of SQSTM1 protein]; U 0126 inhibits the reaction [methylmercuric chloride results in increased expression of SQSTM1 protein] | PMID:27667695 PMID:30769081 PMID:37258240 | Sqstm1 | increases expression | ISO | Sqstm1 (Rattus norvegicus) | 6480464 | CTD | methylmercuric chloride results in increased expression of SQSTM1 mRNA | PMID:20864626 | Sqstm1 | increases expression | ISO | SQSTM1 (Homo sapiens) | 6480464 | CTD | methylmercuric chloride results in increased expression of SQSTM1 mRNA; methylmercuric chloride results in increased expression of SQSTM1 protein | PMID:27667695 PMID:28001369 PMID:34328791 | | ||||||||||||||||||||||
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