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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730855
Species: Homo sapiens
RGD Object: Gene
Symbol: SOD1
Name: superoxide dismutase 1
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SOD1decreases expressionEXP 6480464CTDmethylmercuric chloride results in decreased expression of SOD1 mRNA; methylmercuric chloride results in decreased expression of SOD1 proteinPMID:29581082
SOD1decreases expressionISOSod1 (Rattus norvegicus)6480464CTDmethylmercuric chloride results in decreased expression of SOD1 proteinPMID:29258870 PMID:36813253
SOD1increases expressionISOSod1 (Mus musculus)6480464CTDmethylmercuric chloride results in increased expression of SOD1 mRNAPMID:20061341
SOD1multiple interactionsISOSod1 (Rattus norvegicus)6480464CTDAcetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of SOD1 protein]PMID:36813253
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