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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70373
Species: Homo sapiens
RGD Object: Gene
Symbol: BAX
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BAXincreases expressionEXP 6480464CTDmethylmercuric chloride results in increased expression of BAX mRNAPMID:23179753 PMID:26272509
BAXmultiple interactionsEXP 6480464CTD[NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BAX mRNAPMID:27188386
BAXincreases expressionISOBax (Rattus norvegicus)6480464CTDmethylmercuric chloride results in increased expression of BAX mRNA; methylmercuric chloride results in increased expression of BAX proteinPMID:28821999 PMID:32061141 PMID:35678294
BAXmultiple interactionsISOBax (Rattus norvegicus)6480464CTD1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [methylmercuric chloride results in increased expression of BAX protein]; Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of BAX mRNA]; Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of BAX protein]PMID:32061141 PMID:35678294
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