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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3033
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Smad4
Name: SMAD family member 4
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Smad4decreases expressionISOSMAD4 (Homo sapiens)6480464CTDmethylmercuric chloride results in decreased expression of SMAD4 mRNAPMID:26272509 PMID:28001369
Smad4increases expressionISOSmad4 (Mus musculus)6480464CTDmethylmercuric chloride results in increased expression of SMAD4 mRNAPMID:20061341
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