GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gdnf | decreases expression | EXP | | 6480464 | CTD | methylmercuric chloride results in decreased expression of GDNF protein | PMID:30890323 | Gdnf | multiple interactions | EXP | | 6480464 | CTD | fisetin inhibits the reaction [methylmercuric chloride results in decreased expression of GDNF protein] | PMID:30890323 | Gdnf | decreases expression | ISO | Gdnf (Mus musculus) | 6480464 | CTD | methylmercuric chloride results in decreased expression of GDNF mRNA | PMID:21385734 | Gdnf | multiple interactions | ISO | GDNF (Homo sapiens) | 6480464 | CTD | methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 mRNA]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 protein]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the methylation of NR4A1 promoter]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the phosphorylation of CREB1 protein]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREB1 protein binds to NR4A1 promoter]]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [EZH2 protein binds to NR4A1 promoter]] | PMID:36565944 | | ||||||||||||||||||||||
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