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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2559
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Epo
Name: erythropoietin
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Epodecreases expressionEXP 6480464CTDmethylmercuric chloride results in decreased expression of EPO proteinPMID:31850806
Epomultiple interactionsEXP 6480464CTD2-Methoxyestradiol promotes the reaction [methylmercuric chloride results in decreased expression of EPO protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [methylmercuric chloride results in decreased expression of EPO protein]; cobaltous chloride inhibits the reaction [methylmercuric chloride results in decreased expression of EPO protein]; protocatechuic acid inhibits the reaction [methylmercuric chloride results in decreased expression of EPO protein]PMID:31850806
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