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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349475
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPA1A
Name: heat shock protein family A (Hsp70) member 1A
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPA1Aincreases expressionEXP 6480464CTDmethylmercuric chloride results in increased expression of HSPA1A mRNAPMID:28001369
HSPA1Aincreases expressionISOHspa1a (Mus musculus)6480464CTDmethylmercuric chloride results in increased expression of HSPA1A mRNAPMID:20061341
HSPA1Aincreases expressionISOHspa1a (Rattus norvegicus)6480464CTDmethylmercuric chloride results in increased expression of HSPA1A proteinPMID:36813253
HSPA1Amultiple interactionsISOHspa1a (Rattus norvegicus)6480464CTDAcetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HSPA1A protein]PMID:36813253
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