GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | increases secretion | EXP | | 6480464 | CTD | Rotenone results in increased secretion of IFNG protein | PMID:28903492 | Ifng | multiple interactions | EXP | | 6480464 | CTD | [lipopolysaccharide, E. coli O26-B6 co-treated with IFNG protein] results in increased susceptibility to Rotenone; Rotenone inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 co-treated with IFNG protein] results in increased expression of CYBB mRNA]; Rotenone inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 co-treated with IFNG protein] results in increased expression of HIF1A mRNA]; Rotenone inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 co-treated with IFNG protein] results in increased expression of IL1B mRNA]; Rotenone inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 co-treated with IFNG protein] results in increased expression of IL1B protein]; Rotenone inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 co-treated with IFNG protein] results in increased expression of IL6 mRNA]; Rotenone inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 co-treated with IFNG protein] results in increased expression of IL6 protein]; Rotenone inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Rotenone inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 co-treated with IFNG protein] results in increased expression of PFKP mRNA]; Rotenone inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 co-treated with IFNG protein] results in increased expression of PTGS2 mRNA]; Rotenone inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 co-treated with IFNG protein] results in increased expression of TNF mRNA]; Rotenone inhibits the reaction [[lipopolysaccharide, E. coli O26-B6 co-treated with IFNG protein] results in increased expression of TNF protein]; Rotenone results in increased susceptibility to [lipopolysaccharide, E. coli O26-B6 co-treated with IFNG protein] | PMID:30686998 | Ifng | decreases activity | ISO | IFNG (Homo sapiens) | 6480464 | CTD | Rotenone results in decreased activity of IFNG protein | PMID:19635391 | Ifng | increases expression | ISO | Ifng (Rattus norvegicus) | 6480464 | CTD | Rotenone results in increased expression of IFNG protein | PMID:32115830 PMID:35728354 PMID:35833337 | Ifng | multiple interactions | ISO | Ifng (Rattus norvegicus) | 6480464 | CTD | nardosinone inhibits the reaction [Rotenone results in increased expression of IFNG protein]; nootkatone inhibits the reaction [Rotenone results in increased expression of IFNG protein]; troxerutin inhibits the reaction [Rotenone results in increased expression of IFNG protein] | PMID:32115830 PMID:35728354 PMID:35833337 | Ifng | multiple interactions | ISO | IFNG (Homo sapiens) | 6480464 | CTD | Rotenone inhibits the reaction [IFNG protein affects the localization of STAT1 protein]; Rotenone inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of STAT1 protein] | PMID:15748169 | | ||||||||||||||||||||||
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