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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1331975
Species: Mus musculus
RGD Object: Gene
Symbol: Pomc
Name: pro-opiomelanocortin-alpha
Acc ID: CHEBI:28177
Term: theophylline
Definition: A dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea.
Chemical ID: MESH:D013806
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pomcmultiple interactionsISOPomc (Rattus norvegicus)6480464CTD[Theophylline co-treated with POMC protein] results in increased abundance of Cyclic AMP; INS1 protein inhibits the reaction [[Theophylline co-treated with POMC protein] results in increased abundance of Cyclic AMP]PMID:4306506
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